How Is BRIDGES-NBS different from routine newborn screening?

Routine newborn screening looks for at least 30 to 40 conditions, depending on the state’s newborn screening program.

BRIDGES-NBS is a much broader screen, looking for risks for hundreds of genetic conditions. Both screenings use the same heel-prick blood sample.

Participation in BRIDGES-NBS is voluntary.

Routine Newborn Screening BRIDGES-NBS Genomic Screening
Screens for at least 30–40 conditions Looks for about 800 conditions
Uses a blood spot from heel prick at birth Uses blood from the same heel prick, no additional blood needed
Screens using biochemical markers in the blood. Some states screen for a few conditions using genetic testing Screens using genome sequencing to look for genetic changes in specific genes
Part of routine newborn care in all states/US territories Parent/guardian provides informed consent for participation
Results usually available within 1 week of birth Results usually available within 2-3 months after birth